Problem 37
In a large, randomly mating population, the frequency of the allele (s) for sickle-cell hemoglobin is \(0.028 .\) The results of studies have shown that people with the following genotypes at the beta-chain locus produce the following average numbers of offspring: $$\begin{array}{cc} \text { Genotype } & \text { Average number of offspring } \\ \text {} & \text { offspring produced } \\ \text { SS } & 5 \\ \text { Ss } & 6 \\ \text { ss } & 0 \\ \end{array}$$ a. What will the frequency of the sickle-cell allele (s) be in the next generation? b. What will the frequency of the sickle-cell allele be at equilibrium?
Problem 39
In a large, randomly mating population, the frequency of an autosomal recessive lethal allele is \(0.20 .\) What will the frequency of this allele be in the next generation if all homozygotes die before reproducing?